Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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2,866
Tocris Bioscience™ GSK 2830371
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective allosteric inhibitor of Wip1 phosphatase
| Inhibitors | GSK 2830371 |
|---|---|
| Product Type | GSK 2830371 |
| Molecular Weight (g/mol) | 461.02 |
| Purity | >98% |
2,867
Tocris Bioscience™ XL 413 Hydrochloride
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Potent and selective Cdc7 inhibitor
| CAS | 1169562-71-3 |
|---|---|
| Solubility | Soluble to 20mM in water |
| Purity | >99% |
| Chemical Name or Material | 8-Chloro-2-(2S)-2-pyrrolidinylbenzofuro[3,2-d]pyrimidin-4(3H)-one hydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C14H12ClN3O2.HCl |
| Formula Weight | Observed MW: 326.18 |
2,868
Tocris Bioscience™ 7-Chlorokynurenic acid
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CAS: 18000-24-3 Molecular Formula: C10H6ClNO3
| CAS | 18000-24-3 |
|---|---|
| Molecular Formula | C10H6ClNO3 |
2,869
Tocris Bioscience™ KY 02111
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Inhibits canonical Wnt signaling. Promotes differentiation of human ESCs and iPSCs into cardiomyocytes
| CAS | 1118807-13-8 |
|---|---|
| Chemical Name or Material | N-(6-Chloro-2-benzothiazolyl)-3,4-dimethoxybenzenepropanamide |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C18H17ClN2O3S |
| Formula Weight | Observed MW: 376.86 |
| Assay Percent Range | >99% |
2,870
Tocris Bioscience™ BINA
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CAS: 866823-73-6 Molecular Formula: C30H30O4
| CAS | 866823-73-6 |
|---|---|
| Molecular Formula | C30H30O4 |
2,871
Tocris Bioscience™ AMG 510
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Potent and selective KRASG12C inhibitor
| Target | Ras GTPase Inhibitors |
|---|---|
| CAS | 2252403-56-6 |
| Purity | 0.98 |
| Chemical Name or Material | (1 R)-6-Fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2 S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]pyrido[2,3-d]pyrimidin-2(1 H)-one |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C30H30F2N6O3 |
2,872
Tocris Bioscience™ CGS 12066B dimaleate
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CAS: 109028-10-6 Molecular Formula: C25H25F3N4O8
| CAS | 109028-10-6 |
|---|---|
| Molecular Formula | C25H25F3N4O8 |
2,873
Tocris Bioscience™ MRS 2179 tetrasodium salt
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CAS: 1454889-37-2 Molecular Formula: C11H17N5Na4O9P2
| CAS | 1454889-37-2 |
|---|---|
| Molecular Formula | C11H17N5Na4O9P2 |
2,874
Tocris Bioscience™ KS 176
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Selective BCRP inhibitor
| Inhibitors | KS 176 |
|---|---|
| Product Type | KS 176 |
| Molecular Weight (g/mol) | 405.4 |
| Purity | >98% |
2,875
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Tocris Bioscience™ Geldanamycin
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Tocris Bioscience™ Geldanamycin
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Selective Hsp90 inhibitor
2,876
Tocris Bioscience™ (+)-PD 128907 hydrochloride
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CAS: 300576-59-4 Molecular Formula: C14H20ClNO3
| CAS | 300576-59-4 |
|---|---|
| Molecular Formula | C14H20ClNO3 |
2,877
Tocris Bioscience™ SN 38
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CAS: 86639-52-3 Molecular Formula: C22H20N2O5
| CAS | 86639-52-3 |
|---|---|
| Molecular Formula | C22H20N2O5 |
2,878
Tocris Bioscience™ 4-CMTB
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CAS: 300851-67-6 Molecular Formula: C14H15ClN2OS
| CAS | 300851-67-6 |
|---|---|
| Molecular Formula | C14H15ClN2OS |
2,879
Tocris Bioscience™ Isoguvacine hydrochloride
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CAS: 68547-97-7 Molecular Formula: C6H10ClNO2
| CAS | 68547-97-7 |
|---|---|
| Molecular Formula | C6H10ClNO2 |
2,880
Tocris Bioscience™ NESS 0327
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Ultra-high affinity and selective CB1 antagonist
| Target | Cannabinoid R1/CB1 Antagonists |
|---|---|
| CAS | 494844-07-4 |
| Purity | 98% |
| Chemical Name or Material | 8-Chloro-1-(2,4-dichlorophenyl)-1,4,5,6-tetrahydro-N-1-piperidinyl-benzo[6,7 ]cyclohepta[1,2-c]pyrazole-3-carboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C24H23Cl3N4O |